2017 NCI IMAT PI Meeting header

Active Projects

 

Contact PI/ Project Leader 

Other PI/ Project Leader(s)

Organization Name

Project Title 

AKSAN, ALPTEKIN

N/A

UNIVERSITY OF MINNESOTA

Validation of a Room-Temperature Storage Technique for Plasma/Serum Biospecimens

ANDERSON, KAREN SUE

BLATTMAN,
JOSEPH N

ARIZONA STATE UNIVERSITY-TEMPE CAMPUS

Single Cell Technologies for Rapid Detection of Tumor Heterogeneity

BAILEY,
RYAN C

ORDOG,
TAMAS

UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN

Droplet Microfluidic Platform for Ultralow Input Epigenetics

BHARGAVA, ROHIT

CHEVILLE,
JOHN C

UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN

Translational Molecular and Cellular Imaging Technologies for Prostate Tumor Pathology

BHATNAGAR, PARIJAT

N/A

SRI INTERNATIONAL

Cellular Biofactories for Therapeutic Protein Synthesis in Tumor

BIRTWISTLE, MARC R

N/A

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

Multiplexed, Quantitative Fluorescence Imaging in Tumor Sections

BOMSZTYK, KAROL

N/A

UNIVERSITY OF WASHINGTON

Next Generation Technology to Detect Epigenetic Alterations in Human Tissues

BREUNIG,
JOSHUA JOHN

N/A

CEDARS-SINAI MEDICAL CENTER

A Genetic Toolbox for the Identification and Interrogation of Tumor Cells of Origin, Propagation, and Recurrence from Patient-Derived Oncogenic Drivers

BROWN, JONATHAN QUINCY

N/A

TULANE UNIVERSITY OF LOUISIANA

Improving Biospecimen Quality by Verifying Adequacy at the Point-Of-Acquisition with Ex Vivo Structured Illumination Microscopy

BURGETT, ANTHONY WG

N/A

UNIVERSITY OF OKLAHOMA NORMAN

Mass Spectrometry Detection of Drugs in Single Bladder Cancer Cells from Patients

BURKE, PETER J.

N/A

UNIVERSITY OF CALIFORNIA- IRVINE

High-Throughput On-Chip Platform for Interrogation of Mitochondrial Membrane Potential and Apoptosis

CARON,
MARC G.

N/A

DUKE UNIVERSITY

A Cancer Rainbow Mouse for Simultaneous Assessment of Multiple Oncogenes

CHANG,
HSUEH-CHIA

SENAPATI, SATYAJYOTI;
SHAH, SUNNY SATISH

UNIVERSITY OF NOTRE DAME

A Solid-State Nanopore Mirna Quantification Technology

DAVIS, RONALD WAYNE

N/A

STANFORD UNIVERSITY

Nanoneedle Microrobots for Single Cancer Cell Manipulation and Genome Editing

FAN, RONG

LEVINE,
ROSS L

YALE UNIVERSITY 

Single cell cytokine analysis of circulating malignant hematopoietic cells

GAMCSIK, MICHAEL

N/A

NORTH CAROLINA STATE UNIVERSITY RALEIGH

High-Throughput Screening Under Static or Dynamic Hypoxia

GAO, XIAOHU

N/A

UNIVERSITY OF WASHINGTON

Cancer molecular analysis using quantum dots

GARCIA,
ANDRES J

THOMAS,
SUSAN NAPIER

GEORGIA INSTITUTE OF TECHNOLOGY

uSHEAR Technology for Cancer Cell Purificaiton

GERTZ, JASON

N/A

UNIVERSITY OF UTAH

Development of Enhancer RNA-based Biomarkers in FFPE Tissue

HALL, ADAM ROGER

N/A

WAKE FOREST UNIVERSITY HEALTH SCIENCES

Molecular Detection of DNA Hydroxymethylation for Cancer Screening

HAMMOND, SCOTT M

N/A

UNIV OF NORTH CAROLINA CHAPEL HILL

An optimized design for single copy short hairpin RNAi

HAUN, JERED BRACKSTON

N/A

UNIVERSITY OF CALIFORNIA- IRVINE

Transforming fluorescence lifetime imaging microscopy into a fast and simple platform for high-content molecular analysis

HAYDEN, MELANIE

QUAKE,
STEPHEN R

STANFORD UNIVERSITY

Cell-free tumor DNA in cerebral spinal fluid decodes tumors of the central nervous system

HELD,
JASON M

BIRMAN, VLADIMIR B

WASHINGTON UNIVERSITY

Development of Novel Chemical Probes to Map S- Nitrosylation in Cancer

HERR, AMY ELIZABETH

N/A

UNIVERSITY OF CALIFORNIA BERKELEY

Microfluidic Western Blotting for Targeted Proteomic Analysis of Single Circulating Tumor Cells

IAFRATE, ANTHONY JOHN

N/A

MASSACHUSETTS GENERAL HOSPITAL

Highly Multiplexed FISH for In Situ Genomics

ISSADORE, DAVID AARON

N/A

UNIVERSITY OF PENNSYLVANIA

A micro Hall chip for circulating microvesicle based cancer monitoring

JAHNKE, FRANK

N/A

SONATA BIOSCIENCES, INC.

A New Sample Preparation Method to Delve Deeper into the Proteome

JOHANN, DONALD

TANGREA, MICHAEL

UNIV OF ARKANSAS FOR MED SCIS 

Development and Validation of a Microdissection Method to Advance Precision Medicine in the Clinical Setting

KELLEY, SHANA O

N/A

UNIVERSITY OF TORONTO

Development and validation of nanoparticle-mediated microfluidic profiling approach for rare cell analysis

KESHARI, KAYVAN R.

N/A

SLOAN-KETTERING INST CAN RESEARCH

uCoil NMR platform for robust and high-throughput analysis of in vitro metabolic flux on living cells

KLEIN, ALLON MOSHE

N/A

HARVARD MEDICAL SCHOOL

Droplet microfluidic technology for single cell cancer genomics

KRON, STEPHEN J.

N/A

UNIVERSITY OF CHICAGO

Tag-ChIP-MS for analysis of chromatin-level regulation of DNA repair

KRUMMEL, MATTHEW F

N/A

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO

Living Tumor Biopsies to Interrogate Immune Function and Response to Therapy

LABAER, JOSHUA

N/A

ARIZONA STATE UNIVERSITY-TEMPE CAMPUS

Multiplexed In Solution Protein Array (MISPA) for identifying novel protein interactions in cancer and for early detection of immune responses in pathogen-induced cancers

LAM, KIT S

N/A

UNIVERSITY OF CALIFORNIA AT DAVIS

GESI: a novel technology for functional imaging in living cells

LARMAN, HARRY BENJAMIN

N/A

JOHNS HOPKINS UNIVERSITY

A Highly Multiplexed Gene Expression Platform for Fixed Tissue Specimens

LEVENSON, RICHARD M.

N/A

UNIVERSITY OF CALIFORNIA AT DAVIS

Cancer histology and QC via MUSE: Sample-sparing UV surface-excitation microscopy

LIANG,
FU-SEN

N/A

UNIVERSITY OF NEW MEXICO

Novel Bi-functional Inhibitors Blocking OncomiR Biogenesis

LIN, QIAO

N/A

COLUMBIA UNIV NEW YORK MORNINGSIDE

Validating Rapid Microfluidic Isolation of Personalized Aptamers for Monitoring Minimal Residual Disease in Multiple Myeloma

LIOTTA,
LANCE ALLEN

N/A

GEORGE MASON UNIVERSITY

Protein painting identifies therapeutic targets at protein-protein interfaces

LU, CHANG

N/A

VIRGINIA POLYTECHNIC INST AND ST UNIV

Next-generation MOWChIP-seq for high-throughput epigenomic profiling using clinically relevant samples

MACCOSS, MICHAEL

N/A

UNIVERSITY OF WASHINGTON

Systematic and Comprehensive Sampling of Peptides in Mixtures by Tandem Mass Spectrometry

MALMSTADT, NOAH

ROBERTS, RICHARD W

UNIVERSITY OF SOUTHERN CALIFORNIA

A Target-Directed Reagent Pipeline via Microfluidic mRNA Display

MANALIS, SCOTT R

N/A

MASSACHUSETTS INSTITUTE OF TECHNOLOGY

Single cell growth assay for residual cells in acute lymphoblastic leukemia

MATOUSCHEK, ANDREAS

N/A

UNIVERSITY OF TEXAS, AUSTIN

Development of proteasome adaptors to catalytically deplete specific proteins from cells

MITRAGOTRI, SAMIR S

N/A

UNIVERSITY OF CALIFORNIA SANTA BARBARA

Assessing the risk of UV-induced skin cancer via non-invasive epidermal sampling

MOHS,
AARON M.

N/A

UNIVERSITY OF NEBRASKA MEDICAL CENTER

Tunable Fluorescent Organic Nanoparticles for Cancer Imaging Applications

NAGRATH, SUNITHA

RAMNATH,
NITHYA

UNIVERSITY OF MICHIGAN

High Throughput GO Chip isolation of Lung CTCs for Molecular Diagnosis and Drug Testing

PATTENDEN, SAMANTHA GAIL

DAVIS, IAN J; DAYTON,
PAUL A

UNIV OF NORTH CAROLINA CHAPEL HILL

The application of Enhanced Cavitation to enable DNA and Chromatin Extraction from Archived Tissues

PATTI, GARY JOSEPH

N/A

WASHINGTON UNIVERSITY

Cell-Specific Isotope Labeling to Track Intercellular Metabolite Exchange in Cancer

PENNO, MARGARET B

N/A

JOHNS HOPKINS UNIVERSITY

Pediatric Cancer Salvia Biorepository

PRATX, GUILLEM

N/A

STANFORD UNIVERSITY

High-throughput radionuclide counting and sorting of single cells

QIN, LIDONG

ZU, YOULI

METHODIST HOSPITAL RESEARCH INSTITUTE

High Throughput Single-Cell Phenotype Isolation by Protrusion Analysis Chip (PAC)

QUEIMADO, MARIA DE LURDES

N/A

UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR

A novel molecular assay for early detection and assessment of cancer risk

RAPPAPORT, STEPHEN MORRIS

N/A

UNIVERSITY OF CALIFORNIA BERKELEY

Using Adductomics to Characterize Exposures to Carcinogens

RECHT, MICHAEL

N/A

PALO ALTO RESEARCH CENTER

High-throughput screening platform for cancer drug discovery

REGEV, AVIV

JOHNSON,
BRUCE E.

BROAD
INSTITUTE, INC.

Clinical implementation of single cell tumor transcriptome analysis

ROBINSON, WILLIAM H

N/A

STANFORD UNIVERSITY

Large-Scale Characterization of Anti-Cancer Antibody Responses in Lung Adenocarci

SADEGHI, SAMAN

N/A

UNIVERSITY OF CALIFORNIA LOS ANGELES

Electrochemical Synthesis of Radiopharmaceuticals

SALIPANTE, STEPHEN J

N/A

UNIVERSITY OF WASHINGTON

Advanced development and validation of targeted molecular counting methods for precise and ultrasensitive quantitation

SARAF,
RAVI F

N/A

UNIVERSITY OF NEBRASKA LINCOLN

High Specificity MicroRNA Microarray Analysis without PCR for Cancer Screening and Research

SADEGHI, SAMAN

N/A

UNIVERSITY OF CALIFORNIA LOS ANGELES

Electrochemical Synthesis of Radiopharmaceuticals

SALIPANTE, STEPHEN J

N/A

UNIVERSITY OF WASHINGTON

Advanced development and validation of targeted molecular counting methods for precise and ultrasensitive quantitation

SCARCELLI, GIULIANO

N/A

UNIV OF MARYLAND, COLLEGE PARK

Brillouin confocal microscopy for biomechanical studies of metastatic cascade in 3D microenvironments

SCHULTZ, ZACHARY

N/A

UNIVERSITY OF NOTRE DAME

Online Raman Diagnostics of Oncometabolites

SCHWARTZ, DAVID C.

MA, JIAN

UNIVERSITY OF WISCONSIN-MADISON

Scalable Cancer Genomics via Nanocoding and Sequencing

SEGAL,
DAVID J

N/A

UNIVERSITY OF CALIFORNIA AT DAVIS

CRISPR-based epigenetic modifiers

SEIBEL, ERIC J

N/A

UNIVERSITY OF WASHINGTON

Needle biopsy preservation and preparation for rapid 3D pathology of pancreas

SIMS, PETER ALAN

N/A

COLUMBIA UNIVERSITY HEALTH SCIENCES

Large-Scale Integration of Single Cell RNA-Seq and High- Content Imaging for Analyzing Drug Response in Cancer

SINGH, ANKUR

N/A

CORNELL UNIVERSITY

LETSSGo: Lymphoma-on-chip Engineered Technology for Single-Organoid Sequencing and Genomics

SLATER, JOHN HUNDLEY

N/A

UNIVERSITY OF DELAWARE

A Vascularized, In Vitro, Organotropic Metastasis Model to Generate Dormant Micrometastases

SOELLNER, MATTHEW B

N/A

UNIVERSITY OF MICHIGAN

Exquisitely selective turn-on probes of kinase activation and localization

SOHN, LYDIA L

N/A

UNIVERSITY OF CALIFORNIA BERKELEY

Isolating Circulating Tumor Cells

SOKER, SHAY

N/A

WAKE FOREST UNIVERSITY HEALTH SCIENCES

Bioengineered Lung Tumor Organoids For Development Of Personalized Medicine

SPICER, TIMOTHY PATRICK

N/A

SCRIPPS FLORIDA

Advanced Development and Validation of 3 Dimensional Spheroid Culture of Primary Cancer Cells using Nano3D

SULCHEK, TODD

MCDONALD,
JOHN F

GEORGIA INSTITUTE OF TECHNOLOGY

Label-free microfluidic enrichment of cancer cells from noncancer cells in ascites fluid

TAO, NONGJIAN

N/A

ARIZONA STATE UNIVERSITY-TEMPE CAMPUS

Charge sensitive optical detection for high-throughput study of small molecules

TEMPST, PAUL

N/A

SLOAN-KETTERING INST CAN RESEARCH

Immobilized protease activity tests for developing functional cancer biomarkers

VAN DAM, ROBERT MICHAEL

N/A

UNIVERSITY OF CALIFORNIA LOS ANGELES

High-throughput radiochemistry platform for accelerated discovery and development of novel PET imaging agents for cancer

VANDER GRIEND, DONALD JAMES

COLLIER,
JOEL H

UNIVERSITY OF CHICAGO

Supramolecular matrix materials for prostate cancer cell biology

VO-DINH, TUAN

N/A

DUKE UNIVERSITY

Nanoplasmonics-based molecular analysis tool for molecular biomarkers of cancer

WALTER,
NILS G

N/A

UNIVERSITY OF MICHIGAN

Single-molecule counting of cancer biomarker miRNAs in human biofluids

WANG,
TZA-HUEI

N/A

JOHNS HOPKINS UNIVERSITY

Digital Detection of Tumor-Derived Circulating Methylated DNA

WEISS, GREGORY A.

N/A

UNIVERSITY OF CALIFORNIA-IRVINE

Monitoring Recurrent Bladder Cancer with Electro-Phage Biosensors

WEISSLEDER, RALPH

N/A

MASSACHUSETTS GENERAL HOSPITAL

Analysis of scant cancer cells in fine needle aspirates

WELJIE,
AALIM M

N/A

UNIVERSITY OF PENNSYLVANIA

Determining and enhancing metabolite fitness for metabolomics measurements

WELSH,
JOHN T

N/A

VACCINE RESEARCH INSTITUTE OF SAN DIEGO

A molecular method to determine isoform frequencies in RNA-seq

WILLIAMS, JOHN CHARLES

BROWN, CHRISTINE

BECKMAN RESEARCH INSTITUTE/CITY OF HOPE

In situ Imaging of CAR T-cells

WONG, WESLEY PHILIP

N/A

BOSTON CHILDREN'S HOSPITAL

Single-molecule mechanical detection of protein and microRNA cancer biomarkers

WU, YUN

N/A

STATE UNIVERSITY OF NEW YORK AT BUFFALO

Noninvasive detection of circulating RNAs for lung cancer early detection and prognosis

YATES,
JOHN R

N/A

SCRIPPS RESEARCH INSTITUTE

Measurement of Aberrant Protein Folds in Malignant Cells with Proteomics and Mass Spectrometry

YEAKLEY, JOANNE MULLIGAN

N/A

BIOSPYDER TECHNOLOGIES, INC.

RASL-Seq Expression Profiling of FFPE Tissues

YEH,
HSIN-CHIH

DUNN,
ANDREW K

UNIVERSITY OF TEXAS, AUSTIN

An integrated imaging tool for probing EGFR subcellular trafficking in real time

ZENG, YONG

GODWIN, ANDREW K.;SAMUEL, GLENSON

UNIVERSITY OF KANSAS LAWRENCE

Integrated exosomes profiling for minimally invasive diagnosis and monitoring of cancer

ZHU, HENG

DESAI,
PRASHANT JAYANT

JOHNS HOPKINS UNIVERSITY

Development of a virion display (VirD) array to profile human GPCR interactions

ZILBERBERG, JENNY

LEE, WOO
YOUNG

HACKENSACK UNIVERSITY MEDICAL CENTER

Microfluidic approach for the development of a three- dimensional bone marrow micr

ZIPFEL, WARREN R

N/A

CORNELL UNIVERSITY

Fast interference-based super-resolution microscope for cancer mechanobiology